Surgical treatment of type 1 gastric neuroendocrine tumors: A 20-years single center experience

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Introduction: Gastric neuroendocrine tumors (g-NETs) are rare, differentiated and usually indolent lesions; they include 3 types based on their pathogenesis. Type 1 are usually treated endoscopically according to their size, depth of invasion and presence of lymph-node (LN) metastases, types 3 are generally treated surgically. There is no clear evidence of the most accurate staging strategy for regional LN metastases.

Aim(s): To evaluate the accuracy of 68-Ga DOTA PET for detecting nodal involvement in g-NETs type 1 pts.

Materials and methods: We conducted a retrospective analysis of patients (pts) with type 1 g-NETs treated from 2000 to oct 2021. Endoscopy and CT scan were used for staging. Indication for 68-Ga DOTA PET was NETs larger than 2 cm or suspicious cN+ at CT scan. Endoscopic ultrasound with fine needle biopsy was used selectively. Surgery was indicated for tumors endoscopically unresectable, with cN+ or invasion beyond the submucosa after endoscopic resection.

Conference:

Presenting Author: Bertani E

Authors: Colombo S, Fumagalli Romario U, Pisa E, Spada F, Fazio N,

Keywords: Pet, gastric neuroendocrine tumor, surgery,