The predictive value of 68Ga-DOTANOC, 18F-DOPA, and 18F-FDG PET/CT in patients with paragangliomas

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Introduction: Paragangliomas (PGLs) are rare neuroendocrine tumours with variable clinical outcomes. Early identification of prognostic markers is essential for effective disease management. PET/CT imaging with 68Ga-DOTANOC, 18F-DOPA, and 18F-FDG offers unique insights into tumour biology, respectively.

Aim(s): We investigated the predictive value of 68Ga-DOTANOC, 18F-DOPA, and 18F-FDG PET/CT in patients with PGLs.

Materials and methods: Our study analysed data from 57 consecutive patients with PPGL who underwent 68Ga-DOTANOC, 18F-DOPA or 18F-FDG PET/CT imaging. Each patient underwent baseline assessments and systematic imaging for follow-up. Progression-free survival (PFS) was defined as the interval from the initial PET/CT to the first documented instance of disease progression.

Conference:

Presenting Author: Xu J

Authors: Gao J, Xu J, Liang Y, Chen J, Song S,

Keywords: PET/CT, paraganglioma, prognosis,