The role of microbiome diversity in neuroendocrine tumour (NET) development and progression: Insights from a cohort study

#4602

Introduction: The gut microbiome may influence neuroendocrine tumour (NET) development, particularly gastrointestinal NETs, yet data on this connection within Pakistan are limited. This study explores microbiome diversity’s role in NET progression.

Aim(s): To investigate the association between gut microbiome diversity and NET development and progression, adjusting for demographic and dietary factors.

Materials and methods: A cohort of 60 NET patients and 60 controls was recruited. Gut microbiome profiles were analysed using 16S rRNA sequencing, with diversity indices compared between groups. Clinical data, including tumour stage and grade, were correlated with microbiome profiles, alongside dietary and lifestyle patterns.

Conference:

Presenting Author: Fatima A

Authors: Fatima A,

Keywords: Bacterial imbalance, Prognostic biomarker,