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The Role of Primary Resection and Hepatic Resection in the Management of Metastatic Pancreatic Neuroendocrine Tumors with Irresectable Liver Metastases


Introduction: More than 40% of pancreatic neuroendocrine tumor (PNET) patients have liver metastases (LM) at diagnosis. Whilst it is agreed that, where possible, curative surgery offers the best outcomes, the role of debulking surgery in the context of irresectable LM remains unclear.

Aim(s): To investigate the survival benefits of different surgical treatments of LM.

Materials and methods: Of 111 PNET patients, 53 had LM at diagnosis and were divided into three cohorts: No Resection (NR) n=27, Pancreatic Resection (PR) n=6 and Pancreatic and Liver Resection (PLR) n=11. Median follow-up was 40.2 months.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Mills L, Ramage J, Prachalias A, Srinivasan P, Menon K,

Keywords: liver,

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