The Usefulness of Assessment the Serum Concentrations of Vascular Endothelial Growth Factor (VEGF) and Its Soluble Receptor Type 2 (VEGFR2) in Patients with Neuroendocrine Neoplasm (NEN)

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Introduction: Angiogenesis plays an important role in tumour growth and disease progression. VEGF is a angiogenesis-stimulating factor. VEGFR2 has antiangiogenic properties.

Aim(s): Assessment the usefulness of determining VEGF and VEGFR2 serum concentrations in patients with NEN.

Materials and methods: The study included 82 patients with NEN: 48 women aged 57,17± 12,11 years and 34 men aged 59,56±13,06 years. The control group consisted of 48 healthy sex- and age-matched cases. VEGF and VEGFR2 serum concentrations were mesured using the ELISA method with R&D Systems kits.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Rosiek V, Kos-Kudła B, Zemczak A,

Keywords: neuroendocrine neoplasms, VEGF, VEGFR2,

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