Abstract Library
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ENETS Abstract Search
#2168 Phase II Trial of Cabozantinib in Patients with Carcinoid and Pancreatic Neuroendocrine Tumors
Introduction: Activation of VEGFR2 and MET is implicated in driving growth of NET. Cabozantinib inhibits VEGFR2, MET, AXL, RET.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Chan J, Faris J, Murphy J, Blaszkowsky L, McCleary N,
Keywords: cabozantinib, pancreatic neuroendocrine tumor, carcinoid, phase II,
Introduction: Angiogenesis plays an important role in tumour growth and disease progression. VEGF is a angiogenesis-stimulating factor. VEGFR2 has antiangiogenic properties.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author:
Authors: Rosiek V, Kos-Kudła B, Zemczak A,
Keywords: neuroendocrine neoplasms, VEGF, VEGFR2,
Introduction: Improving our understanding of the molecular biology of GEP-NETs represents a key challenge in the treatment of these rare tumors.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Berardi R
Authors: Berardi R, Pagliaretta S, Rinaldi S, Morgese F, Partelli S,
Keywords: Angiogenesis, Prognosis, Neuroendocrine tumors,
Introduction: Microvasculature of liver metastatic pancreatic neuroendrocrine tumors (LM-PNETs) are unknown.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Han X
Authors: Han X, Hexige S, Lou W,
Keywords: Liver metastatic PNET, microvessels, basal microvilli, VEGFR2, pVEGFR2,
Introduction: Clinical studies have suggested efficacy of VEGF pathway inhibitors in the treatment of advanced neuroendocrine tumors (NETs).
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Qian Z
Authors: Qian Z, Ter-Minassian M, Chan J, Imamura Y, Hooshmand S,
Keywords: VEGF, bevacizumab, NET survival,