The value of 68Ga-Exendin-4 PET/CT for benign and metastatic insulinoma

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Introduction: Insulinoma is the most common functional pancreatic neuroendocrine tumour which is difficult to locate by conventional imaging. 68Ga-exendin-4 PET/CT is a promising technique for detecting benign insulinomas but is not definite for metastatic insulinomas.

Aim(s): Our study aimed to determine the value of 68Ga-exendin-4 PET/CT for benign and metastatic insulinoma.

Materials and methods: We prospectively enrolled the patients with recurrent hypoglycaemia regardless of the existing pancreatic neuroendocrine tumour (pNET). According to our study protocols, 68Ga-exendin-4 PET/CT was performed 60 and 120 minutes after injection. 68Ga-DOTANOC PET/CT was performed in 7 days. The final results were confirmed by surgery or follow-up.

Conference:

Presenting Author: Xu J

Authors: Xu J, Liang Y, Huang D, Chen J, Song S,

Keywords: insulinoma, 68Ga-exendin-4, PET/CT,