The value of biomarkers in gastroenterology neuroendocrine neoplasms

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Introduction: Neuroendocrine neoplasms (NENs) are heterogeneous which include neuroendocrine tumors (NETs), neuroendocrine carcinomas [NECs including small cell carcinoma (SCCs) and large cell carcinomas (LCCs)] and mixed neuroendocrine non-neuroendocrine neoplasm (MiNENs).

Aim(s): Investigating value and relationship between Rb and DLL3 as biomarkers of NENs in different subtypes and primary sites.

Materials and methods: We collected gastroenterology NEN patients from the Second Affiliated Hospital of Zhejiang University and performed immunohistochemistry (IHC) in each patient. Two pathologists check the IHC results independently.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Cai W

Authors: Cai W, Qi Y, Kai S, Hu H, Mao J,

Keywords: Rb, DLL3, Biomarker, neuroendocrine neoplasm,