Abstract Library

#4414 Impact of chromogranin A expression on clinicopathological characteristics and prognosis in patients with gastrointestinal tumours exhibiting neuroendocrine differentiation

Introduction: Pathological diagnosis of neuroendocrine differentiation (NED) relies on histomorphological assessment and specific markers, including chromogranin A (CgA) and synaptophysin (Syn). Previous studies indicate that tumours with a high proportion of CgA (+) exhibit increased malignancy and aggressiveness in neuroendocrine tumours, suggesting that CgA may serve as a prognostic marker.

Conference:

Presenting Author: Liang T

Authors: Wang W, Jiang K, Liu X, Zhao L, Yu Z,

Keywords: neuroendocrine differentiation, gastric cancer, colorectal cancer, chromogranin A,

#4390 FDG uptake in lung neuroendocrine tumours and its association with tumour characteristics and prognosis

Introduction: The utility of fluorodeoxyglucose positron emission tomography (FDG-PET) in the evaluation of lung neuroendocrine tumours (L-NETs) remains debated.

Conference:

Presenting Author:

Authors: Twito O, Muzykovskaia E, Frenkel M,

Keywords: lung neuroendocrine tumour, imaging, FDG-PET,

#4245 Carcinoid heart in neuroendcrine tumor – Experience of medical departement oncology Oran, Algeria

Introduction: The carcinoid heart is present in approximately 20% of cases at the diagnosis of carcinoid dyndrome in neuroendocrine tumors, and will occur in approximately 50% of patients during follow-up. The consequence is the appearance of stenosing and/or leaking valvular diseases, responsible, eventually, right or left ventricular dysfunction and severe heart failure. Only surgical valve replacement treatment seems to be able to improve the prognosis, but at the cost of significant perioperative morbidity and mortality.

Conference:

Presenting Author: Kaid M

Authors: Kaid M, Bengueddach A, Bennaoum A, Kehili H, Bereksi-Reguig F,

Keywords: carcinoid heart disease, somatostatin,

#4226 Pancreatic neuroendocrine tumors – Epidemiological profile and surgical aspects

Introduction: Pancreatic neuroendocrine tumors (NET) are rare tumors, with an incidence of less than 0.5 cases per 100,000 people, PTNE represents 5% of pancreatic tumors, surgical treatment has a central place because it is the only treatment potentially curative if the resection is complete.

Conference:

Presenting Author:

Authors: Bennaoum S, Kaid M,

Keywords: pancreatic neuroendocine tumor surgery,

#4225 Digestive neuroendocrine tumors – Retrospective study and experience of the general surgery department of EHU Oran

Introduction: Neuroendocrine tumors are rare tumors and represent 1% of all digestive tumors, their incidence has seen a constant increase in recent decades, possibly linked to better diagnostic methods and better knowledge of these tumors. Surgery remains the only curative treatment for localized endocrine tumors. The rarity and heterogeneity of these tumors makes their management difficult and explains the low number of randomized studies and the associated low level of evidence.

Conference:

Presenting Author:

Authors: Bennaoum S, Kaid M,

Keywords: surgery, neuroendcrine digestive tumor,