Abstract Library

#4465 RET Lys666Asn has low MEN2-related tumours penetrance but may be associated with pheochromocytoma

Introduction: Multiple Endocrine Neoplasia type 2 (MEN2) is caused by germline pathogenic variants (PVs) in the RET proto-oncogene, leading to medullary thyroid carcinoma (MTC), pheochromocytoma, and primary hyperparathyroidism (PHPT). RET c.1998G>C, p.Lys666Asn is a rare PV, with 33 cases described thus far, and is associated with low penetrance of MEN2-related tumours, but its clinical significance remains incompletely understood.

Conference:

Presenting Author: Halperin R

Authors: Halperin R, Peshes-Yaloz N, Tirosh A, Twito O,

Keywords: MEN2, pheochromocytoma, hyperparathyroidism, medullary thyroid carcinoma,

#4390 FDG uptake in lung neuroendocrine tumours and its association with tumour characteristics and prognosis

Introduction: The utility of fluorodeoxyglucose positron emission tomography (FDG-PET) in the evaluation of lung neuroendocrine tumours (L-NETs) remains debated.

Conference:

Presenting Author:

Authors: Twito O, Muzykovskaia E, Frenkel M,

Keywords: lung neuroendocrine tumour, imaging, FDG-PET,

#3527 Appendiceal neuroendocrine neoplasms diagnosed during pregnancy: A case series and review of the literature

Introduction: Although appendicitis occurs in approximately 1:1000 pregnancies, appendiceal neuroendocrine neoplasm (ANEN) diagnosis during pregnancy is very rare. Data on presentation, treatment and prognosis is scarce.

Conference:

Presenting Author: Twito O

Authors: Twito O, Akirov A, Rosenblum R, Herzberg D, Oleinikov K,

Keywords: Appendix, neuroendocrine neoplasm, pregnancy,

#2953 Temporal Trends in Incidence, Presentation and Work-Up of Neuroendocrine Neoplasms of the Appendix

Introduction: Although temporal trends in incidence and prognosis of neuroendocrine neoplasms have been described in the literature, data regarding trends in Appendiceal Neuroendocrine Neoplasms (ANENs) is limited.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Twito O

Authors: Twito O, Klein N, Paran H, Avital S, Kravtsov V,

Keywords: appendix, neuroendocrine neoplasms, hemicolectomy, prognosis, temporal trends,

#2950 Hemicolectomy for Neuroendocrine Neoplasms of the Appendix - Is It Really Necessary?

Introduction: Appendical neuroendocrine neoplasms (ANENs) are rare. Limited data is available regarding prognosis and optimal treatment strategy in those tumors

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Twito O, Klein N, Paran H, Avital S, Kravtsov V,

Keywords: appendix, neuroendocrine neoplasms, prognosis, hemicolectomy,