Abstract Library

#4606 Neuroendocrine mess – Ectopic Cushing syndrome and severe hypokalaemia

Introduction: Cushing Syndrome (CS) is the condition resulting from hypercortisolaemia. Ectopic Cushing Syndrome (ECS) is responsible for up to 20% of all CS cases. Pancreatic neuroendocrine neoplasms (pNEN) are responsible for 10-20% of those cases.

Conference:

Presenting Author:

Authors: Corrêa Figueira C, Alves H, Bento A, Cardoso Gomes C, Oliveira A,

Keywords: Pancreatic neuroendocrine neoplasm, Hepatic neuroendocrine metastasis, Paraneoplastic syndrome, Cushing syndrome, Ectopic Cushing syndrome,

#4472 Paraneoplastic cerebellar degeneration relates to lung neuroendocrine tumour

Introduction: Neurological Paraneoplastic syndromes related to cancer are infrequently,

Conference:

Presenting Author:

Authors: González Devia D, Roa Culma L, Martínez Rubio C, Zafra Sierra M, Cañon Solano D,

Keywords: Paraneoplastic Syndrome, Paraneoplastic Cerebellar Degeneration, Neuroendocrine Tumour, Lung Neuroendocrine Tumour, CARP 8 antibody,

#4459 Sequential alkylating therapy and pembrolizumab induce near-complete response in high tumour mutational burden pancreatic neuroendocrine tumour: A case report

Introduction: Traditional treatment for neuroendocrine tumours (NETs), including surgery, somatostatin therapy, and targeted therapy, often fails in advanced disease. Alkylating therapy can increase tumour mutational burden (TMB), and the recent KEYNOTE-158 study approved pembrolizumab for advanced solid tumours with a high TMB.

Conference:

Presenting Author:

Authors: Paranjpe I, Hornbacker K, Vadde S, Fisher G, Shaheen S,

Keywords: pancreatic neuroendocrine tumour, immunotherapy, pembrolizumab, tumour mutational burden, TMB,

#3352 Exacerbation of Necrolytic Migratory Erythema after 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy

Introduction: Necrolytic migratory erythema (NME) is an uncommon skin disorder which is characterized by deep erythematous plaques with superficial blistering, erosions and crusts. NME is a cutaneous manifestation of glucagonoma. Glucagonoma syndrome is a paraneoplastic disease, caused by an excessive secretion of glucagon by pancreatic alpha cells.

Conference:

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Vanden Bulcke A, Curvers S, de Haes P, de Hertogh G,

Keywords: glucagonoma, necrolytic migratory erythema, PRRT, 177Lu-DOTATATE, neuroendocrine tumor, pancreas,

#3321 Calcitonin secreting neuroendocrine neoplasms of the lung: A systematic review

Introduction: Calcitonin (CTN) secreting neuroendocrine neoplasms (NEN) of the lung are rare, with few cases reported in the literature. Differentiating between medullary thyroid carcinoma (MTC) and ectopic source of calcitonin secretion can represent a complex diagnostic conundrum for managing physicians with cases of unnecessary thyroidectomy reported in the literature.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Llewellyn D

Authors: Llewellyn D, Srirajaskanthan R, Guy C, Ramage J, Dimitriadis G,

Keywords: Calcitonin, Ectopic, lung, NEN, systematic review,