Validation of NEP-D score as a prognostic index in bronchial carcinoid tumors

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Introduction: The development of prognostic scores able to classify patients with Bronchial Carcinoid (BC) according to clinical outcomes may help guide treatment selection. The NEP- score was found to be useful to stratify survival probability in patients with well-differentiated neuroendocrine neoplasms (NENs). According to multiple factors (age, primary tumor site, presence of metastasis, Ki-67, presence of functioning status and prior surgical removal of the primary tumor) NEP- score stratifies patients into different risk groups. The NEP-score at diagnosis (NEP-D score) is a derived score that could be calculated at diagnosis and does not consider the appearance of new metastases during follow-up.

Aim(s): We aim to verify the applicability and the prognostic value of the NEP-D score in a BC cohort.

Materials and methods: We retrospectively evaluated the NEP-D score in a series of 35 BC patients from 2009 to 2018. Patients were subdivided according to their vital status (alive or not) after 3±1 years.

Conference:

Presenting Author:

Authors: Medici M, Gagliardi I, Zanata I, Borges de Souza P, Ambrosio M,

Keywords: Bronchial Carcinoid, Neuroendocrine neoplasm, NEP-Score, Prognosis, Survival,