Abstract Library

#2147 Nutritional Assessment and Vitamin Deficiencies in Patients with NETs

Introduction: As a result of disease or related to its management, patients with neuroendocrine tumours may have altered gut or pancreatic function that can cause nutritional deficiencies.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Lim S, Reynolds M, Rees D, Chaudhry R, Blackhouse J,

Keywords: Nutrition, Dietetics, Malnutrition, Vitamin Deficiency, Screening,

#1245 Identification of Response Predictors to Temozolomide-Based Chemotherapy

Introduction: Capecitabine and temozolomide are active in the treatment of metastatic pNETs, with response rates ranging from 30% to 70%. Several small retrospective series have suggested that MGMT deficiency may predict response to temozolomide, however expression of MGMT has not been validated as a predictive biomarker. Cytotoxic chemotherapy is thought to be most active in aggressive tumors, however the ki-67 index has not been formally evaluated as a predictive factor. It is unclear whether chromosomal instability (which correlates with alternate lengthening of telomeres) predicts response.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Strosberg J

Authors: Strosberg J, Cives M, Brelsford M, Black M, Meeker A,

Keywords: ki67, MGMT, ALT, chromosomal instability, temozolomide, capecitabine, pNET,

#318 The SEER as a Prophet: Epidemiological Analysis as a Harbinger of Evolving Priorities in Gastroenteropancreatic Neuroendocrine Neoplasia

Introduction: Previous epidemiology analysis of tumor registries established that gastroenteropancreatic neuroendocrine neoplasms (GEP-NETs) were both more prevalent, and more malignant, than previously recognized.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Lawrence B, Gustafsson B, Chan A, Svejda B, Kidd M,

Keywords: black, carcinoids, epidemiology, GEP-NET, incidence, pancreas, rectal, SEER, survival, USA,