Abstract Library

#1770 Cytokines as Predictive Factors of Response to Somatostatin Analogues in Patients with Neuroendocrine Tumour

Introduction: The somatostatin analogues are a major therapeutic advance in neuroendocrine tumor (NET) treatment and have multiple modulatory effects on the immune system.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Sciammarella C

Authors: Sciammarella C, Grimaldi A, Circelli L, Modica R, Pizza G,

Keywords: cytokines, neuroendocrine, cell,

#1109 Expression and Role of the CXCR4/CXCL12/CXCR7 Axis and Crosstalk with the mTOR Pathway in Neuroendocrine Tumors (NETs)

Introduction: Chemokine receptor CXCR4 has been shown to signal on mTOR pathway in gastric and renal cancer. CXCR4 interacts with the chemokine CXCL12 to exert proliferative and chemotactic effects.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Sciammarella C

Authors: Sciammarella C, Circelli L, Guadagno E, Tafuto S, Del Basso De Caro M,

Keywords: chemokine, mtor, nets, clinical outcome.,

#860 Expression and Prognostic Role of CXCR4/CXCL12/CXCR7 and mTOR Pathways in Neuroendocrine Tumors (NETs)

Introduction: The chemokine receptor CXCR4 interacts with the ligand CXCL12 to exert proliferative and chemotactic effects. CXCR4 activates mTOR through phosphorylation of its two effectors downstream:4EBP1and S6K

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Circelli L, Sciammarella C, Faggiano A, Tafuto S, Pezzullo L,

Keywords: Chemokine, mTOR, NETs, clinical outcome,