Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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ENETS Abstract Search

#3705 First results from IEO 676 clinical study of PRRT in neuroendocrine tumors – Is there still a space for Y-90-DOTATOC?

Introduction: IEO 676 is a prospective phase II study of Peptide Receptor Radionuclide Therapy (PRRT) with Y-90-DOTATOC in progressive G1, G2, G3, neuroendocrine patients. PRRT has been in use since the late 1990s, with the introduction of 90Y-DOTATOC, which allowed objective responses in 10-30% of treated patients.

Conference:

Presenting Author: Grana C

Authors: Grana C, Papi S, Clerici I, Rocca P, Spada F,

Keywords: PRRT, Y-90-DOTATOC, NET,

#477 Glucagon-Like Peptide 1 Receptor (GLP-1R) Imaging for the Preoperative Localization of Benign Insulinomas in 30 Patients

Introduction: Biochemical diagnosis of endogenous hyperinsulinemic hypoglycemia is straightforward. Surgical removal of an insulinoma is hampered by difficulties to localize it using conventional radiological procedures. In vitro data suggest that human insulinoma cells exhibit a high density of GLP-1R. 111In-exendin-4 is an 111In labeled GLP-1R agonist that binds with high affinity to GLP-1R and may be helpful in localizing insulinomas.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Christ E, Forrer F, Wild D, Clerici T, Braendle M,

Keywords: insulinoma, GLP-1 receptor imaging,