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#4383 Clinical and biological heterogeneity of grade 2 gastroenteropancreatic neuroendocrine neoplasms (GEP NENs): Prognostic significance of the 10% Ki-67 index cutoff and implications for treatment strategies

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are a diverse group of neoplasms with varying prognoses. Grade 2 (G2) tumours, with a Ki-67 index between 3%-20%, present management challenges due to their intermediate behaviour, with evidence suggesting distinct outcomes between Ki-67

Conference:

Presenting Author: Massironi S

Authors: Massironi S, Coltro L, Gallo C, Preatoni P, Dell' Anna G,

Keywords: Neuroendocrine neoplasm, Ki-67 Index, Grade 2 Neuroendocrine Tumour, Neoplasm Grading, Tumour Heterogeneity, Progression-Free Survival (PFS), Peptide Receptor Radionuclide Therapy,