Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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#4383 Clinical and biological heterogeneity of grade 2 gastroenteropancreatic neuroendocrine neoplasms (GEP NENs): Prognostic significance of the 10% Ki-67 index cutoff and implications for treatment strategies

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are a diverse group of neoplasms with varying prognoses. Grade 2 (G2) tumours, with a Ki-67 index between 3%-20%, present management challenges due to their intermediate behaviour, with evidence suggesting distinct outcomes between Ki-67

Conference:

Presenting Author: Massironi S

Authors: Massironi S, Coltro L, Gallo C, Preatoni P, Dell' Anna G,

Keywords: Neuroendocrine neoplasm, Ki-67 Index, Grade 2 Neuroendocrine Tumour, Neoplasm Grading, Tumour Heterogeneity, Progression-Free Survival (PFS), Peptide Receptor Radionuclide Therapy,

#4221 Assessing the frequency of type I gastric neuroendocrine neoplasms in autoimmune atrophic gastritis: A multi-center study in Italy

Introduction: In autoimmune atrophic gastritis (AAG), mucosa morpho-functional changes lead to hypo-achlorhydria, hypergastrinemia, and enterochromaffin-like (ECL) cells proliferation, escalating the risk of type I gastric neuroendocrine neoplasms (gNENs). Longitudinal studies on the AAG-gNENs association are scanty.

Conference:

Presenting Author: Gallo C

Authors: Massironi S, Gallo C, Lahner E, Sciola V, Cavalcoli F,

Keywords: neuroendocrine tumor, atrophic gastritis, autoimmune gastritis, gastrin,

#3999 Exploring the biological and clinical heterogeneity of grade 2 pancreatic neuroendocrine tumors: Insights into diagnosis, prognosis, and therapeutic targets

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs) show heterogeneous behavior, mainly related to their grade (G), nevertheless small well-differentiated G1 and G2 lesions are usually approached the same conservative way.

Conference:

Presenting Author:

Authors: Gallo C, Lorenzo Andrea C, Pietro I, Sara M,

Keywords: pancreas, neuroendocrine, survival, grading,

#3864 Efficacy and safety of capecitabine and temozolomide (CAPTEM) in advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) – A systematic review and metanalysis

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) are heterogeneous tumors, with multiple therapeutic options for advanced stages. The combination of capecitabine and temozolomide (CAPTEM) is increasingly used for advanced GEP-NEN, but evidence on results is sparse.

Conference:

Presenting Author: Tacelli M

Authors: Tacelli M, Massironi S, Gallo C, Bina N, Stornello C,

Keywords: chemotherapy, pfs, progression-free survival, adverse events,

#3861 Incidence and prevalence of gastric neuroendocrine tumors in patients with chronic atrophic autoimmune gastritis

Introduction: The incidence of type I gastric neuroendocrine neoplasms (gNEN) has increased substantially over the past 50 years, although studies evaluating the association with chronic autoimmune atrophic gastritis (CAAG) in the long term have been inconsistent.

Conference:

Presenting Author: Gallo C

Authors: Gallo C, Laffusa A, Elvevi A, Mass S,

Keywords: atrophic gastritis, autoimmune gastritis, gastrin, neuroendocrine tumor,