Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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#4383 Clinical and biological heterogeneity of grade 2 gastroenteropancreatic neuroendocrine neoplasms (GEP NENs): Prognostic significance of the 10% Ki-67 index cutoff and implications for treatment strategies

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are a diverse group of neoplasms with varying prognoses. Grade 2 (G2) tumours, with a Ki-67 index between 3%-20%, present management challenges due to their intermediate behaviour, with evidence suggesting distinct outcomes between Ki-67

Conference:

Presenting Author: Massironi S

Authors: Massironi S, Coltro L, Gallo C, Preatoni P, Dell' Anna G,

Keywords: Neuroendocrine neoplasm, Ki-67 Index, Grade 2 Neuroendocrine Tumour, Neoplasm Grading, Tumour Heterogeneity, Progression-Free Survival (PFS), Peptide Receptor Radionuclide Therapy,

#4221 Assessing the frequency of type I gastric neuroendocrine neoplasms in autoimmune atrophic gastritis: A multi-center study in Italy

Introduction: In autoimmune atrophic gastritis (AAG), mucosa morpho-functional changes lead to hypo-achlorhydria, hypergastrinemia, and enterochromaffin-like (ECL) cells proliferation, escalating the risk of type I gastric neuroendocrine neoplasms (gNENs). Longitudinal studies on the AAG-gNENs association are scanty.

Conference:

Presenting Author: Gallo C

Authors: Massironi S, Gallo C, Lahner E, Sciola V, Cavalcoli F,

Keywords: neuroendocrine tumor, atrophic gastritis, autoimmune gastritis, gastrin,

#3999 Exploring the biological and clinical heterogeneity of grade 2 pancreatic neuroendocrine tumors: Insights into diagnosis, prognosis, and therapeutic targets

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs) show heterogeneous behavior, mainly related to their grade (G), nevertheless small well-differentiated G1 and G2 lesions are usually approached the same conservative way.

Conference:

Presenting Author:

Authors: Gallo C, Lorenzo Andrea C, Pietro I, Sara M,

Keywords: pancreas, neuroendocrine, survival, grading,

#3864 Efficacy and safety of capecitabine and temozolomide (CAPTEM) in advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) – A systematic review and metanalysis

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) are heterogeneous tumors, with multiple therapeutic options for advanced stages. The combination of capecitabine and temozolomide (CAPTEM) is increasingly used for advanced GEP-NEN, but evidence on results is sparse.

Conference:

Presenting Author: Tacelli M

Authors: Tacelli M, Massironi S, Gallo C, Bina N, Stornello C,

Keywords: chemotherapy, pfs, progression-free survival, adverse events,

#3856 Duodenal gastric metaplasia and duodenal neuroendocrine neoplasms – More than a simple coincidence?

Introduction: Duodenal gastric metaplasia (DGM) is considered a precancerous lesion. No data are available regarding its possible role as a risk factor for duodenal neuroendocrine neoplasms (dNENs).

Conference:

Presenting Author: Gallo C

Authors: Massironi S, Rossi R, Milanetto A, Andreasi V, Campana D,

Keywords: duodenal gastric metaplasia, duodenal neuroendocrine neoplasm, epidemiology, risk factor,