Abstract Library

#4643 Characterisation of patients with progressive digestive NET during PRRT (LUTA-CHEC): A multicentre study from the Groupe des Tumeurs Endocrines

Introduction: PRRT with 177Lu-DOTATATE is a major treatment for metastatic digestive NETs. Most patients have prolonged progression-free survival, but around 20% experience early progression.

Conference:

Presenting Author: Haissaguerre M

Authors: Haissaguerre M, Hadoux J, Tlili G, Deshayes E, Lacombe M,

Keywords: GEP-NET, PRRT, early tumour progression,

#4573 Digestive neuroendocrine tumours: Patterns, pathways, and progress in personalised management

Introduction: Digestive neuroendocrine tumours (NETs), though rare, are increasingly diagnosed with their incidence rising. Histopathological examination is crucial for diagnosis and grading, based on cell differentiation and proliferation index. Often diagnosed late due to non-specific symptoms, these tumours may present with hormone hypersecretion. Updated classifications now allow better risk stratification and tailored treatments. Advances in imaging, particularly PETscans with somatostatin analogues have improved NET diagnosis and monitoring.

Conference:

Presenting Author: Bensetti Houari A

Authors: Bensetti Houari A, Remouche H, Belkharoubi K,

Keywords: Digestive neuroendocrine tumour, octreoscan, multidisciplinary approach,

#4460 Digestive neuroendocrine tumours G1 and G2: Experience of the medical oncology department at the Oran University Hospital Establishment 1st November 1954

Introduction: The histological classification of neuroendocrine tumours (NETs) remains complex, and their grading is a major prognostic factor, essential for guiding appropriate management. Moreover, NETs raise unresolved histogenetic questions. The treatment of grade 1 (G1) NETs primarily relies on somatostatin analogues, while grade 2 (G2) NETs, being more heterogeneous, may require management that includes chemotherapy or targeted therapy.

Conference:

Presenting Author:

Authors: Kehili H, Bengueddache A, Boumansour N, Larbi Bounsbia L, Bechikh A,

Keywords: Digestive Neuroendocrine Tumour, Grade 1, Grade 2, Somatostatin Analogue,

#3773 Pancreatic neuroendocrine tumors in Oran – Epidemiological, histological and therapeutic aspects

Introduction: Pancreatic neuroendocrine tumors (pNET) are rare, they represent third of digestive NETs. Their incidence is increasing with a rate that has been multiplied by 5 over the past 20 years to reach 0.6 cases/100,000. This increase is probably related to better detection of this type of tumor. The discovery is often fortuitous or following a non-specific symptomatology which depends on the seat of the tumor. They are often the cause of mainly hepatic metastases. Only surgery at an early stage allows a good evolution. Few data are available on pNETs in our country.

Conference:

Presenting Author:

Authors: Boumansour N, Khalifa S, Kehili H, Bengueddache A, Tabeti B,

Keywords: pancreas, neuroendocrine tumor, epidemiology, histology,

#3771 Epidemiological profile and survival of neuroendocrine tumors of the ampulla of Vater

Introduction: Duodenal neuroendocrine tumors are rare, they represent nearly 2% of digestive NETs. Their incidence is increasing due to better detection. The diagnosis is often late because of the non-specific symptomatology of the tumor. The 5-year survival of duodenal NETs is 68% when the tumor is diagnosed at an early stage.

Conference:

Presenting Author:

Authors: Boumansour N, Saidi M, Khalifa S, Kehili H, Bengueddache A,

Keywords: Vater ampulla, neuroendocrine tumor, Epidemiology, Survival,