Abstract Library

#100 Mammalian target of rapamycin (mTOR) expression analysis and therapeutic approach in lung and gastroenteropancreatic poorly differentiated endocrine carcinoma (PDEC)

Introduction: PDEC clinically include gastroenteropancreatic PDEC, small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC). These tumors are clinically similar and aggressive and they are usually treated with platinum compounds. mTOR signalling pathway has emerged as a promising target for well-differentiated endocrine carcinoma therapy. Because of varying behavior, PDEC are usually excluded from clinical trials employing the mTOR inhibitor RAD001.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Catena L, Milione M, Pusceddu S, Ducceschi M, Avarino M,

Keywords: poorly differentiated endocrine carcinoma, mTOR, RAD001,

#75 Carcinoid and carcinoid syndrome: analysis of 110 cases from a single insitute

Introduction: Carcinoid syndrome (CS) often presents with flushing, diarrhea and carcinoid heart disease (CHD).

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Ducceschi M, Platania M, Valente M, Franceschelli L, Pietrantonio F,

Keywords: carcinoid, carcinoid syndrome, flushing, diarrhea,