Abstract Library

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#383 Everolimus and Octreotide LAR in Neuroendocrine Tumors: An I.T.M.O. (Italian Trials in Medical Oncology) Group Study

Introduction: Everolimus has shown antitumor activity in pancreatic neuroendocrine tumors (NETs) and it seems to work synergistically with octreotide.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Bajetta E, Catena L, Biondani P, Fazio N, Giuffrida D,

Keywords: Everolimus, Octreotide LAR, neuroendocrine tumors,

#350 RAD001 and Octreotide LAR as first-line treatment of well differentiated neuroendocrine tumors: an I.T.M.O. (Italian Trials in Medical Oncology) group study

Introduction: RAD001 has shown antitumor activity in pancreatic neuroendocrine tumors (NETs) and it seems to work synergistically with somatostatine analogues.

Conference:

Presenting Author:

Authors: Catena L, Biondani P, Fazio N, Giuffrida D, Ricci S,

Keywords: neuroendocrine tumors, everolimus, carcinoid,

#100 Mammalian target of rapamycin (mTOR) expression analysis and therapeutic approach in lung and gastroenteropancreatic poorly differentiated endocrine carcinoma (PDEC)

Introduction: PDEC clinically include gastroenteropancreatic PDEC, small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC). These tumors are clinically similar and aggressive and they are usually treated with platinum compounds. mTOR signalling pathway has emerged as a promising target for well-differentiated endocrine carcinoma therapy. Because of varying behavior, PDEC are usually excluded from clinical trials employing the mTOR inhibitor RAD001.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Catena L, Milione M, Pusceddu S, Ducceschi M, Avarino M,

Keywords: poorly differentiated endocrine carcinoma, mTOR, RAD001,

#98 Long-term follow-up analysis of lung carcinoid tumors: retrospective monoinstitutional evaluation

Introduction: Detection of prognostic factors of bronchopulmonary carcinoid (BPCs) tumors is complicated due to the rare frequency of this malignancy.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Pusceddu S, Catena L, Buzzoni R, Valente M, Formisano B,

Keywords: carcinoid, lung cancer, neuroendocrine, pulmonary,