Abstract Library
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Introduction: Somatostatin receptor (SSTR) overexpression is a unique feature of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), which establish the basis for both diagnosis and therapy. SSTR status can be evaluated by immunohistochemical staining (IHC) and 68Ga-DOTATATE PET/CT.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Yu J
#2800 Thymosin Beta 4 Is an Autocrine Mitogen for Neuroendocrine Tumour Cells
Introduction: The most commonly used NET marker chromogranin A, has a sensitivity between 60-90% and a specificity of less than 50%, hence better NET markers are needed. Previous secretome analysis using BON1, NCI-H727 and SHP-77 cell lines has led to the discovery of various candidate NET markers. One such marker is Thymosin Beta 4 (TB4). TB4 is a small 43 amino acid intracellular peptide first isolated from bovine thymus tissue.TB4 or its oxidised form TB4SO are thought to play a role in various aspects of cancer biology including tumour invasion, metastasis and apoptosis.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Balasundaram P, Beaumont N, Liang S, Cuenco J, Lu X,
Keywords: neuroendocrine tumour, biomarkers, signalling,
#2043 Combination of Surgery and Ethanol Ablation in a MEN-2A Patient
Introduction: MEN-2A is an autosomal dominant syndrome characterized by pheochromocytoma, medullary thyroid carcinoma and hyperparathyroidism.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Fang Z
Authors: Fang Z, Tan H, Wang Y, Cai X, Luo J,
Keywords: Men-2a, pheochromocytoma, ethanol ablation,
Introduction: A few previous studies have shown that nomograms can predict the survival rates of patients with neuroendocrine neoplasms (NENs).
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Wei W
Authors: Wei W, Cheng F, Jie C, Zhiwei Z, Ye C,
Keywords: Gastroenteropancreatic Neuroendocrine Neoplasms, Nomogram, Prognosis,
Introduction: The multicenter studies of large-volume database about gastroenteropancreatic neuroendocrine neoplasms(GEP-NENs) patients is rare in China.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Cheng F
Authors: Cheng F, Wei W, Zhiwei Z,
Keywords: gastroenteropancreatic neuroendocrine neoplasms, treatment, prognosis, China,