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#16 Endoglin as indicator of metastatic neuroendocrine tumors of the pancreas

Introduction: Neuroendocrine tumors of the pancreas are rare, highly vascularized tumors. Endoglin, a Transforming Growth Factor-β co-receptor, is a marker for angiogenic endothelial cells. Angiogenesis is required for tumor progression and the development of metastases. Recently, endoglin expression was found to be a prognostic marker in pancreatic carcinomas. However, the role of endoglin in neuroendocrine pancreatic tumors has so far not been studied.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Kuiper P, Verspaget H, de Jonge-Muller E, Hawinkels L, Biemond I,

Keywords: endoglin, pancreatic neuroendocrine tumor, angiogenesis, metastases,