Abstract Library

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ENETS Abstract Search

#1032 Clinico-Biological and Histological Predictive Factors and Markers of Response to Everolimus in Neuroendocrine Tumors

Introduction: Several systemic treatments are available for metastatic neuroendocrine Tumors (NETs), including everolimus, but there is no predictive factor of response to these treatments.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Walter T

Authors: Benslama N, Bollard J, Vercherat C, Roche C, Hervieu V,

Keywords: neuroendocrine tumors, everolimus, markers, p-p70S6K,

#180 Microvessel Density and Prognosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETS)

Introduction: The role of anti-angiogenic agents in GEP-NETS remains to be established. CD105 (Endoglin) identifies the TGF-ß1 receptor which is expressed on endothelial cells involved in tumor angiogenesis.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Soares C, Bettencourt H, Preto J, Soares P, Pinto-de-Sousa J,

Keywords: gastroenteropancreatic neuroendocrine tumors, angiogenesis, microvessel density, CD105, Endoglin,

#16 Endoglin as indicator of metastatic neuroendocrine tumors of the pancreas

Introduction: Neuroendocrine tumors of the pancreas are rare, highly vascularized tumors. Endoglin, a Transforming Growth Factor-β co-receptor, is a marker for angiogenic endothelial cells. Angiogenesis is required for tumor progression and the development of metastases. Recently, endoglin expression was found to be a prognostic marker in pancreatic carcinomas. However, the role of endoglin in neuroendocrine pancreatic tumors has so far not been studied.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Kuiper P, Verspaget H, de Jonge-Muller E, Hawinkels L, Biemond I,

Keywords: endoglin, pancreatic neuroendocrine tumor, angiogenesis, metastases,