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#3168 Endocrine neoplasias and non-endocrine neoplasias associated with primary aldosteronism

Introduction: Primary aldosteronism (PA) is the main cause of secondary arterial hypertension (AH) of endocrine origin (1). Clinical presentation may include resistance to treatment for AH, hypokalemia, with the autonomous secretion of aldosterone. Somatic mutations and epigenetic factors are the most frequent etiologies (2). Adrenal tumors may be a characteristic of MEN1 syndrome (3). Some case reports have associated endocrine neoplasms with PA; however, the real prevalence of this association is unknown (3).

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Jaramillo Chacón H, López Panqueva R, Cañón Solano D,

Keywords: primary hyperaldosteronism, primary aldosteronism, neuroendocrine tumor, endocrine tumor, neoplasia,

#2885 Ectopic Neuroendocrine Carcinoma: An Occult Source of ACTH

Introduction: About 250 cases of ectopic ACTH-producing neuroendocrine carcinoma (ACTH-NEC) have been reported; however metastatic ACTH-NEC of unknown primary is very rare. Usually are characterized by having a large cell, small cell, poorly differentiated or anaplastic cell, and Ki-67 index between 40-90%.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Alvaréz Figueroa J, Aguirre Matallana D, Cañón Solano D,

Keywords: Ectopic ACTH production, Cushing’s syndrome, Neuroendocrine carcinoma, Paraneoplastic Cushing syndrome, Ectopic Cushing´s syndrome,