Abstract Library

#3265 Assessment of hormonal levels as prognostic markers and of their optimal cut-offs in small intestinal neuroendocrine tumors grade 2

Introduction: Multianalytes might be used to monitor small intestinal neuroendocrine tumors (siNETs) Grade 2 in the future, but blood chromogranin A (CgA) and urine 5HIAA are still widely used in clinical praxis.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Papantoniou D, Grönberg M, Landerholm K, Welin S, Ziolkowska B,

Keywords: Chromogranin A, 5HIAA, small intestinal neuroendocrine tumor, biomarker, carcinoid, cut-offs,

#3184 Immune heterogeneity and cascade of changes in subtypes of pancreatic neuroendocrine tumors

Introduction: Previously, we published four molecular subtypes of pancreatic neuroendocrine tumors (PanNETs) - met-like primary (MLP)-1 and -2, intermediate and insulinoma- like with different clinical and molecular characteristics. While immunotherapy trials are on-going in PanNETs, the immune landscape of this disease is largely unknown.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Sadanandam A

Authors: Sadanandam A, Young K, Lawlor R, Ragulan C, Patil Y,

Keywords: pancreatic neuroendocrine tumor, immune microenvironment, viral-mimicry pathway, pancreatic cancer, computational methods, T cells, macrophages, immunotherapy, B cells, complement pathway, interferon signalling, STING pathway, hypoxia, necroptosis, tumor ,

#3075 Telotristat Makes Significant Difference on Symptoms and Serotonin Levels in a Population with Widespread GI-NET and Severe Carcinoid Syndrome

Introduction: In spite of new treatments like PRRT or everolimus there is a clinical need for systemic therapies that complement SSAs (somatostatin analogs) and antidiarrheal agents in the treatment of carcinoid syndrome, a late stage problem in s-i-NET. Telotristat is a promising addition to our therapeutic arsenal.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Linder Ekberg K,

Keywords: telotristat, carcinoid syndrome, metastasized GI-NET,

#2938 Rectal Neuroendocrine Tumor with Concomitant Erdheim-Chester Disease: A Rare Case Report

Introduction: Rectal neuroendocrine tumor (NET), a type of rare tumor, is rather rarer when accompanied by non-Langerhans cells histiocytosis named Erdheim-Chester disease (ECD).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Zhang Y, Liu M, Chen L, Guo Y, Chen M,

Keywords: rectal neuroendocrine tumor, Erdheim-Chester disease.,

#2930 Treatment of the Pinealoma: Experience from a Rare Case

Introduction: Pinealoma is an extremely rare type of neuroendocrine tumor without evidence-based systemic therapy.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Zhang Y, Liu M, Chen L, Guo Y, Chen M,

Keywords: pinealoma, octreotide, interferon.,