Abstract Library

#3145 Reduction of serum insulin levels and diazoxide doses as an effect of PRRT in patients with severe hypoglycemia due to primary non-operative insulinoma

Introduction: Severe hypoglycaemia in a course of inoperable insulinoma may be life-threating and it is not always well controlled even by high doses of diazoxide, which in some cases cause a significant toxicity. Nowadays, other forms of effective therapy are not available - use of protein kinase inhibitors (everolimus, sunitynib) sometimes bring satisfactory effect but is often associated with the risk of serious side effects. Use of Peptide receptor radionuclide therapy (PRRT), characterized by relatively low toxicity, is not widely used.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Opalińska M

Authors: Opalinska M, Sowa-Staszczak A, Al Maraih I, Kostecka-Matyja M, Hubalewska-Dydejczyk A,

Keywords: PRRT, insulinoma, NEN,

#2076 Pancreatic Neuroendocrine Tumor in Polish Population with MEN 1 Syndrome

Introduction: The multiple endocrine neoplasia type 1 (MEN 1) is a genetically conditioned syndrome which is characterised by usually mild parathyroid and pituary gland adenomas, pancreatic neuroendocrine tumor (pNET). The last appear in 30-70% of MEN 1 patients being main life-threatening manifstation among MEN 1 patients. The prognosis might improve by presymptomatic tumor detection.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Soczomski P, Jurecka-Lubieniecka B, Rogozik N, Grajewska-Ferens M, Michalik B,

Keywords: Multiple endocrine neoplasia, Menin, Pancreatic Neuroendocrine Tumor, Polish population,

#348 Management of Multiple Endocrine Neoplasia Type 1 in Patients with Pancreatic Neuroendocrine Tumors

Introduction: Screening for MEN-1 is an integral part of examination of patients with pNETs because revelation of this hereditary pathology radically influences tactics of treatment.

Conference:

Presenting Author:

Authors: Vasiliev I, Egorov A, Musaev G, Kondrashin A, Gurevich L,

Keywords: MEN-1 syndrome, pancreatic neuroendocrine tumor,

#179 A Variant Pancreatic Insulinoma in MEN1 Syndrome Characterized by Normoglycemia/Normoinsulinemia but Abnormal C-Peptide and Abnormal Proinsulin Levels

Introduction: Insulinoma associated w/ hyperinsulinemia is frequent in functioning pancreatic NET in MEN 1. We report on familial variant insulinoma w/ normoglycemia/norminsulinemia, but abnormal C-peptide and proinsulin.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Ahmed M, Al Qaraawi A, Al Faifi J,

Keywords: MEN 1 syndrome, insulinoma, genetic analysis,

#61 Multiple tumors in patients with pancreatic neuroendocrine tumours: morphological and immunohistochemical characteristics

Introduction: Pancreatic islet cell tumors occur in 80% of patients with MEN 1. Tumors are often multicentric. They often produce multiple peptides and biogenic amines.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Gurevich L, Egorov A, Askenderova E, Kubyshkin V, Kochatkov A,

Keywords: pancreatic islet cell tumor, pancreatic neuroendocrine tumor, MEN 1 syndrome, neuroendocrine marker, hormone,