Abstract Library

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ENETS Abstract Search

#1044 Trends in Neuroendocrine Tumor in Friuli Venezia Giulia in the Last 20 Years

Introduction: Epidemiological study conducted on patients (pts) with neuroendocrine tumors (NEN) at the regional referral center for Endocrinology and Metabolic Diseases of the Udine Hospital, Italy.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Grimaldi F

Authors: Grimaldi F, Cipri C, Motta C, Pellegrini M, Piussi S,

Keywords: survival,

#701 High Expression of Mammalian Target of Rapamycin (mTOR) in NF1-Related Periampullary Neuroendocrine Tumors

Introduction: Neurofibromatosis type 1 (NF1) is a rare inherited disorder associated with cutaneous lesions and neoplasms in the nervous and gastroenteropancreatic systems, including periampullary NETs. NF1-coded protein, neurofibromin, is a tumor suppressor that negatively regulates the mammalian target of rapamycin (mTOR). Preclinical in vitro and in vivo studies demonstrated a constitutive activation of mTOR pathway associated with significant antineoplastic effects of mTOR inhibitors in NF1-related glial tumor models.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Razzore P

Authors: Razzore P, Volante M, Russolillo N, Motta M, Lacidogna G,

Keywords: NF1, periampullar NETs, mTOR ,

#335 Dosimetry with 111In-octreotide and Coinfusion of Amino Acids in the Prediction of Nephrotoxicity in Neuroendocrine Tumors after PRRT with 90Y-DOTATOC

Introduction: Kidneys are the critical organs in PRRT. A dosimetry protocol was implemented in an ongoing study to estimate the biological effective dose (BED) on the kidneys after 90Y-DOTATOC therapy.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Van Binnebeek S, Baete K, Vanbilloen B, Terwinghe C, Mottaghy F,

Keywords: PRRT, 90y-DOTATOC, dosimetry, 111in-octreotide, amino acids,