#4668
Predictive factors of postoperative recurrence in patients with neuroendocrine tumour of the lung: Prospective analysis of clinicopathologic features and radiomics
Introduction:
In localised and locally advanced forms neuroendocrine tumours (NETs) of the lung radical surgical resection represents the standard of care, several clinicopathologic factors are potentially associated with recurrence of disease.
Conference:
Presenting Author:
Paravani P
Authors:
Paravani P,
Russo F,
Mazzilli R,
Zamponi V,
Mancini C,
Keywords:
radiomics,
predictive role,
rfs,
lung,
lung net,
#4228
Evaluation of the impact of indoleamine 2,3-deoxygenase (IDO) enzyme activity in neuroendocrine tumors (NETs)
Introduction:
Indoleamine 2,3-deoxygenase (IDO) enzyme, by inducing L-tryptophan (Trp) depletion and L-kynurenine (kyn) accumulation, contributes to the formation of an immunosuppressive microenvironment. Some studies highlighted that patient with cancer in treatment with immune checkpoint inhibitors (ICI) and with low Kyn/Trp values showed a better PFS and OS, but there are no data for NETs.
Conference:
Presenting Author:
Mancini C
Authors:
Mancini C,
Mazzilli R,
Zamponi V,
Motta C,
Salerno G,
Keywords:
neuroendocrine tumor,
IDO enzyme,
Kyn/Trp ratio,
immunotherapy,
#4201
Prospective analysis of the risk of post-surgical recurrence in lung typical carcinoid
Introduction:
In localized/locally advanced forms of NET, radical surgical resection represents the standard of care.
Conference:
Presenting Author:
Authors:
Paravani P,
Russo F,
Mazzilli R,
Zamponi V,
Mancini C,
Keywords:
Lung typical carcinoid,
recurrence-free-survival,
Ki-67%,
Male sex,
Mitotic Index,
TTF-1,
Surgery,
#3877
Short fasting test as a reliable and effective tool to diagnose insulinoma
Introduction:
Insulinomas are pancreatic NETs presenting with hypoglycaemia. Current guidelines for its diagnosis require a prolonged fasting test (72 hours), which implies hospitalization and is difficult to perform. It has been reported that up to 85% of insulinomas are diagnosed within a 24h fasting period.
Conference:
Presenting Author:
Mikovic N
Authors:
Mikovic N,
Mazzilli R,
Zamponi V,
Russo F,
Faggiano A,
Keywords:
insulinoma,
neuroendocrine pancreatic tumor,
functioning NET,
hypoglycaemia,
