Abstract Library

#4668 Predictive factors of postoperative recurrence in patients with neuroendocrine tumour of the lung: Prospective analysis of clinicopathologic features and radiomics

Introduction: In localised and locally advanced forms neuroendocrine tumours (NETs) of the lung radical surgical resection represents the standard of care, several clinicopathologic factors are potentially associated with recurrence of disease.

Conference:

Presenting Author: Paravani P

Authors: Paravani P, Russo F, Mazzilli R, Zamponi V, Mancini C,

Keywords: radiomics, predictive role, rfs, lung, lung net,

#4201 Prospective analysis of the risk of post-surgical recurrence in lung typical carcinoid

Introduction: In localized/locally advanced forms of NET, radical surgical resection represents the standard of care.

Conference:

Presenting Author:

Authors: Paravani P, Russo F, Mazzilli R, Zamponi V, Mancini C,

Keywords: Lung typical carcinoid, recurrence-free-survival, Ki-67%, Male sex, Mitotic Index, TTF-1, Surgery,

#3877 Short fasting test as a reliable and effective tool to diagnose insulinoma

Introduction: Insulinomas are pancreatic NETs presenting with hypoglycaemia. Current guidelines for its diagnosis require a prolonged fasting test (72 hours), which implies hospitalization and is difficult to perform. It has been reported that up to 85% of insulinomas are diagnosed within a 24h fasting period.

Conference:

Presenting Author: Mikovic N

Authors: Mikovic N, Mazzilli R, Zamponi V, Russo F, Faggiano A,

Keywords: insulinoma, neuroendocrine pancreatic tumor, functioning NET, hypoglycaemia,

#3586 Grading diagnostic accuracy of EUS Tissue Acquisition in pancreatic neuroendocrine tumors: A systematic review and meta-analysis

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs), are a form of neoplasms arising from cells of the endocrine and nervous systems. Grading (G) is one of the most important decisional factor for therapy as is associated with prognosis, overall survival and disease free survival decrease. Endoscopic ultrasound fine needle-aspiration/biopsy (EUS-FNA/B) is the gold standard for diagnosing PanNENs and Ki67 evaluation, but data regarding accuracy and concordance with post-surgical histological examination are scanty and heterogeneous.

Conference:

Presenting Author:

Authors: Tacelli M, Bina N, Crinò S, Facciorusso A, Barresi L,

Keywords: endoscopic ultrasound, net, ki67, who, misclassification,

#3476 A phase II single arm trial evaluating the efficacy and safety of Temozolomide for second-line treatment of neuroendocrine carcinomas progressing after first-line platinum-based therapy

Introduction: Second-line treatment for neuroendocrine carcinoma (NEC) have been investigated in prospective trials, with only few prospective trials ongoing. Therefore, there is no consensus on the second-line regimen to use in patients with progressive NEC. These patients have generally a poor performance status (PS) and the tolerance to combination therapy is low. Metronomic temozolomide showed, in retrospective trials, a good safety and efficacy profile.

Conference:

Presenting Author:

Authors: Cannella L, von Arx C, Bracigliano A, Pizzolorusso A, Antonella D,

Keywords: neuroendocrine, temozolomide, NEC, Treatment,