Abstract Library

#3482 PANDORA-2 protocol - Intervention study to improve quality of life in patients with small (≤2 cm) non-functional pancreatic neuroendocrine tumors

Introduction: Current guidelines changed the treatment strategy for small (≤2cm) non-functioning pancreatic neuroendocrine tumors (NF-pNET) from tumor resection to an active surveillance strategy. The previous PANDORA-1 (2021) study showed excellent clinical outcomes after a median follow-up of 17 months, where 89% of patients had pNETs without any tumor growth and only 3% of patients had tumor growth leading to a resection. Despite these results, the quality of life (QoL) was decreased at baseline and during follow-up. Furthermore, there was suboptimal adherence to the advised surveillance protocol.

Conference:

Presenting Author: Chen J

Authors: Chen J, Heidsma C, Engelsman A, Nieveen van Dijkum E,

Keywords: neuroendocrine, pancreatic, quality of life, ≤2 cm, non-functional, protocol,

#3429 International survey on opinions and use of minimally invasive surgery in small bowel neuroendocrine neoplasms

Introduction: Although minimally invasive surgery is becoming the standard technique in gastrointestinal surgery, implementation for small bowel neuroendocrine neoplasms (SB-NEN) is lagging behind.

Conference:

Presenting Author: Kaçmaz E

Authors: Kaçmaz E, Engelsman A, Bemelman W, Tanis P, Nieveen van Dijkum E,

Keywords: minimally invasive surgery, small bowel neuroendocrine neoplasm,

#3428 Indocyanine green fluorescence guided resection of neuroendocrine liver metastases: A proof-of-concept study

Introduction: Even though the relative indolent character of neuroendocrine neoplasms, untreated NELM have a detrimental impact on survival outcomes. Therefore, complete resection is recommended if technically possible.

Conference:

Presenting Author: Kaçmaz E

Authors: Kaçmaz E, Slooter M, Tanis P, Nieveen van Dijkum E, Swijnenburg R,

Keywords: neuroendocrine liver metastasis, fluorescence guided surgery, indocyanine green,

#3102 Fluorescence angiography guided resection of small bowel neuroendocrine neoplasms with mesenteric lymph node metastases

Introduction: Surgery for small bowel neuroendocrine neoplasms (SB-NEN) might result in vascular compromise of the remaining bowel due to resection of lymph node metastases in close proximity to main mesenteric vessels. Fluorescence angiography (FA) has been described as a safe technique to assess perfusion during gastro-intestinal surgery.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Kaçmaz E, Slooter M, Nieveen van Dijkum E, Tanis P, Engelsman A,

Keywords: fluorescence angiography, indocyanine green, neuroendocrine neoplasm, small bowel, lymph node metastases,

#3099 Evaluating nationwide application of minimally invasive surgery for small bowel neuroendocrine neoplasms and the impact on survival

Introduction: Open surgery for small bowel neuroendocrine neoplasms (SB-NEN) is still considered standard-of-care, mainly because of frequently encountered multifocality and central mesenteric masses.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Kaçmaz E, Klümpen H, Bemelman W, Nieveen van Dijkum E, Engelsman A,

Keywords: survival, laparoscopy, surgery, small intestine, neuroendocrine neoplasm,