Abstract Library

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#900 Renal Effects of Streptozocin: Preliminary Results of the STREPTOTOX Study

Introduction: Based on old studies, Streptozocin (STZ) is known to have some renal toxicity.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Mitry E

Authors: Mitry E, Brixi H, Lecomte T, Lombard-Bohas C, Seitz J,

Keywords: digestive neuroendocrine tumors, streptozotocin, nephrotoxicity, chemotherapy,

#127 Sunitinib for the treatment of advanced, progressive pancreatic neuroendocrine tumors

Introduction: Sunitinib is an oral, multitargeted tyrosine kinase inhibitor approved for use in advanced renal cell carcinoma and imatinib-resistant/intolerant gastrointestinal stromal tumors. Investigations of sunitinib in the RIP1-Tag2 mouse model and in phase I/II clinical trials provide evidence of antitumor activity against pancreatic neuroendocrine tumors (NET).

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Raymond E

Authors: Raymond E, Seitz J, Bang Y, Borbath I, Lombard-Bohas C,

Keywords: Sunitinib, phase III, pancreatic neuroendocrine tumor ,