Abstract Library

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#4335 Late nephrotoxicity of peptide receptor radionuclide therapy (PRRT) and impact of selected factors – A single centre cohort study

Introduction: The most common side effect of radioligand therapy is renal damage, early or late. However, limited data exist for the long-term side effects and impact of additional risk factors on renal function in patients treated with PRRT.

Conference:

Presenting Author: Sygula A

Authors: Sygula A, Kropinska A, Kotecka-Blicharz A, Gawlik T, Wycislik M,

Keywords: Neuroendocrine tumour, PRRT, nephrotoxicity, yttrium-90, lutetium-177,

#3612 Cystatin C may serve as a suitable blood-based biomarker to monitor renal functional decline in patients scheduled for peptide receptor radionuclide therapy

Introduction: Peptide receptor radionuclide therapy (PRRT) for treating somatostatin receptor (SSTR)-positive tumors may be associated with nephrotoxicity.

Conference:

Presenting Author: Hasenauer N

Authors: Hasenauer N, Hartrampf P, Weich A, Higuchi T, Schirbel A,

Keywords: sstr, theragnostics, prrt, renal, nephrotoxicity,

#3516 177Lutetium-Peptide Receptor Radionuclide Therapy (PRRT) safety assessment in patients with refractory Gastro-Entero-Pancreatic Neuroendocrine Tumors (GEP NETs)

Introduction: 177Lu-PRRT became an established therapeutic modality in inoperable or metastatic NETs, demonstrating substantial survival benefits and reassuring safety profile. Dosimetry of Organs-At-Risk [OAR, kidneys, bone marrow (BM) and spleen] and malignant lesions ensures to further optimize its safety and efficacy.

Conference:

Presenting Author: van Bogaert C

Authors: van Bogaert C, Mileva M, Marin G, Levillain H, Artigas-Guix C,

Keywords: PRRT, Safety, Dosimetry, Prospective trial,

#1388 Nephrotoxicity after PRRT with 177Lu-DOTA-Octreotate

Introduction: Renal toxicity may occur after Peptide Receptor Radionuclide Therapy (PRRT). Risk factors have been identified for renal toxicity after 90Y based PRRT.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Bergsma H

Authors: Bergsma H, Konijnenberg M, Van der Zwan W, Kam B, Teunissen J,

Keywords: PRRT, Kidneys, Toxicity, Dosimetry,

#900 Renal Effects of Streptozocin: Preliminary Results of the STREPTOTOX Study

Introduction: Based on old studies, Streptozocin (STZ) is known to have some renal toxicity.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Mitry E

Authors: Mitry E, Brixi H, Lecomte T, Lombard-Bohas C, Seitz J,

Keywords: digestive neuroendocrine tumors, streptozotocin, nephrotoxicity, chemotherapy,