Abstract Library

#1448 Distribution of T-Cell Infiltrate in G1, G2 and G3 NENs

Introduction: The identification of T-cell infiltrate and the expression of inhibitory molecules in the tumor microenvironment could lend support to the use of immunotherapy in the treatment of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs).

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Milione M

Authors: Milione M, Pellegrinelli A, Centonze G, Dominoni F, Pusceddu S,

Keywords: Ki-67, T-cells, NEN,

#1219 Changes in Neuroendocrine Tumor Microenvironment with WHO Tumor Grading

Introduction: The microenvironment of neuroendocrine neoplasias (NEN) in view of tumor grading (WHO classification of 2000 und 2010) has not yet been validated. Both classifications distinguish between well and poorly differentiated neuroendocrine tumors, including proliferation rate, mitotic index and histomorphology. The WHO classification of 2000 further evaluates tumor location, size, angioinvasion, invasion of the muscle layer, functionally active tumors and metastases.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Cameron S

Authors: Cameron S, Skupin J, Füzesi L,

Keywords: NEN stroma,