Abstract Library
Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.
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ENETS Abstract Search
#4141 BRAF/MEK combination treatment in a patient with BRAF mutated neuroendocrine carcinoma
Introduction: Preclinical studies indicate that BRAF V600E mutation is a druggable target in neuroendocrine carcinomas (NEC). Indeed, there are a few case reports that describe clinical response from BRAF inhibitor treatment of colorectal NEC.
Conference:
Presenting Author: Zhang L
Authors: Falkman L, Zhang L, Welin S, Crona J,
Keywords: Neuroendocrine carcinoma, BRAF V600E, Dabrafenib, Trametinib,
#1891 GSK3: A Novel Therapeutic Target in NETs?
Introduction: GSK3 is a serine/threonine-kinase that plays a critical role in cancer. In neuroendocrine tumours (NETs) GSK3 is regularly overactivated.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Nölting S
Authors: Weis C, Aristizabal Prada E, Maurer J, Spöttl G, Grossman A,
Keywords: GSK3-inhibition, neuroendocrine tumors, combination treatment,
Introduction: CLARINET trial has proven the antiproliferative effects of LAN in patients with non-functioning gastro-entero-pNETs. However, the combination of LAN with targeted therapies is widely used in clinical practice and should be further evaluated.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Casanovas O
Authors: Martínez-López A, Pinto J, Teulé A, Salazar R, Culler M,
Keywords: Lanreotide, pNET,
Introduction: Therapeutic options for patients with advanced progressive GEP-NET are still limited.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Raderer M
Authors: Raderer M, Hörsch D, Lahner H, Rinke A, Denecke T,
Keywords: GEP-NET, Lanreotide, Temozolomide,
Introduction: The combination of Streptozotocin with 5-FU has been used during the past decades in our institution as the first-line treatment in pancreatic NETs with low to moderate proliferation.
Conference: 8th Annual ENETSConcerence (2011)
Presenting Author:
Authors: Antonodimitrakis P, Skogseid B, Hurtig M, Oberg K, Granberg D,
Keywords: Streptozotocin, 5-FU, endocrine pancreatic tumors, progression-free survival, side effects,