Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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#3457 Relevant prognostic factors in patients with stage IV small intestine neuroendocrine neoplasms

Introduction: There are only few, but controversial data on the prognostic role of upfront primary tumor resection and mesenteric lymph node dissection (PTR) in patients with stage IV small intestinal neuroendocrine neoplasia (SI-NEN).

Conference:

Presenting Author:

Authors: Maurer E, Heinzel-Gutenbrunner M, Rinke A, Rütz J, Figiel J,

Keywords: stage 4 small intestine neuroendocrine neoplasm, primary tumor resection, survival, peptide receptor radionuclide therapy,

#3263 Prognostic factors in curative resected locoregional small intestine neuroendocrine neoplasms

Introduction: Small intestinal neuroendocrine neoplasms (SI-NEN) are rare and only about 40% of patients are diagnosed without distant metastases.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Maurer E

Authors: Bartsch D, Maurer E, Evers M, Ramaswamy A, Rinke A,

Keywords: SI-NEN, stage 3, surgery,

#1891 GSK3: A Novel Therapeutic Target in NETs?

Introduction: GSK3 is a serine/threonine-kinase that plays a critical role in cancer. In neuroendocrine tumours (NETs) GSK3 is regularly overactivated.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Nölting S

Authors: Weis C, Aristizabal Prada E, Maurer J, Spöttl G, Grossman A,

Keywords: GSK3-inhibition, neuroendocrine tumors, combination treatment,

#874 The pan-TRK Inhibitor GNF5837 Inhibits Cell Viability and Akt and MAPK Signaling in Human Neuroendocrine GOT1 Tumor Cells

Introduction: The tropomyosin receptor kinase family (TRKA, TRKB, TRKC) effects tumor cell growth in various models. Recent preclinical studies in neuroendocrine carcinoma of the lung cell lines have shown that Trk receptors might be a therapeutic target for neuroendocrine neoplasias.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Heinzle V, Reuther C, Spöttl G, Maurer J, Göke B,

Keywords: neuroendocrine tumor, trk receptor,

#739 Aspirin Inhibits Cell Viability and mTOR Signalling in Neuroendocrine Tumor Cells

Introduction: Patients with multiple endocrine neoplasia (MEN) type 1 develop pancreatic NETs as well as thymic and bronchus carcinoids. Aspirin has been reported to inhibit mTOR signalling and exhibit antitumoral activity in colorectal cancer cells. So far, no data with aspirin on NETs have been published.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Spampatti M, Vlotides G, Spöttl G, Maurer J, Göke B,

Keywords: neuroendocrine tumor, MEN-1, aspirin, mTOR,