#3415
The PEI-Q paradox: Qualitative assessment of exocrine function in NET patients treated with SSAs
Introduction:
Somatostatin-analogues (SSAs) are first-line treatment of unresectable, symptomatic neuroendocrine tumors (NETs), though can cause pancreatic exocrine insufficiency (PEI). PEI symptoms of diarrhoea, bloating, and steatorrhea overlap with those of NETs (carcinoid sequelae), and both have a negative impact on quality of life. The Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) can be used to assess PEI; however, we hypothesise that the score will be unreliable in SSA-induced PEI due to concurrent improvement of carcinoid symptoms.
Conference:
Presenting Author:
Hall L
Authors:
Hall L,
Powell-Brett S,
Thompson O,
Bradley E,
Smith S,
Keywords:
Pancreatic Exocrine Insufficiency (PEI),
Neuroendocrine Tumor (NET),
Patient Reported Outcome,
#2819
Occurrence of Pancreatic Exocrine Insufficiency in Patients with Advanced Neuroendocrine Tumours Treated with Somatostatin Analogue
Introduction:
Neuroendocrine neoplasia (NENs) are heterogeneous tumours caracterized by a relatively indolent rate of growth. Usually, in G1 and G2 GEP-NENs, first-line therapy is SSAs, considering their efficacy, good safety profile, and antiproliferative effects. SSA treatment inhibits the production and excretion of pancreatic enzymes and PEI is known to be an adverse effect of SSA treatment.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Rinzivillo M
Authors:
De Felice I,
Rinzivillo M,
Pratesi M,
Magi L,
Annibale B,
Keywords:
Pancreatic Exocrine Insufficiency,
#249
Management of Insulinomas: Perioperative and Long-term Outcomes Following Enucleations and Pancreatic Resections in 198 Patients
Introduction:
Enucleation represents the procedure of choice for the treatment of insulinomas. Considering the site and the number of lesions, however, formal pancreatic resection may be necessary.
Conference:
8th Annual ENETSConcerence (2011)
Presenting Author:
Authors:
Boninsegna L,
Zerbi A,
Crippa S,
Bettini R,
Capitanio V,
Keywords:
insulinoma,
enucleation,
pancreatic resection,
tumor recurrence,
diabetes,
exocrine insufficiency,
