Abstract Library

#4169 Germline mutation spectrum of neuroendocrine tumors

Introduction: Neuroendocrine tumors (NETs) are rare and highly heterogeneous tumors. Some specific hereditary syndromes enhance the incidence of NETs, suggesting that germline variation may contribute to neuroendocrine tumorigenesis. However, germline genetic variants in Chinese NET patients remain unclear.

Conference:

Presenting Author:

Authors: Sun Y, Tan H, Dong L, Jiang L, Zhao H,

Keywords: germline mutation, neuroendocrine tumor, genetic,

#3623 Characteristics of clinical features of MEN1-associated and sporadic insulinomas – One clinical center experience

Introduction: Insulinomas are usually small, benign tumors that can be radically treated surgically. They may occur as sporadic or be associated with hereditary syndromes, (mainly MEN1 syndrome). In such cases, they may differ in clinical presentation including risk of recurrence and dissemination after curative surgery, which translates into long-term therapy effects.

Conference:

Presenting Author:

Authors: Opalinska M, Gilis-Januszewska A, Morawiec-Sławek K, Kurzyńska A, Sowa-Staszczak A,

Keywords: MEN1, insulinoma, sporadic insulinoma, MEN1 insulinoma,

#3576 Patterns of family history of cancer and associated risk of developing neuroendocrine tumors: A cross-sectional study

Introduction: Except for known hereditary syndromes (mostly, multiple endocrine neoplasia type I and von Hippel Lindau), familial clustering of cancers in patients (pts) with neuroendocrine neoplasms (NEN) is scarcely reported.

Conference:

Presenting Author: Viapiana P

Authors: Viapiana P, Dias C, Cruz Formiga M, Simões Riechelmann R,

Keywords: neuroendocrine tumor, family history,

#2961 Our Experience Using a New Scoring System to Detect Disease Recurrence after Curative Surgical Resection of Well-Differentiated Pancreatic Neuroendocrine Tumors

Introduction: For patients with nonfunctioning pNET  ≥20 mm in size without distant metastasis, complete surgical resection is recommended as the primary curative strategy. Effective follow‐up programs are designed to detect recurrence at an early stage, given that treatment of limited disease has the most favorable outcome. However, data on post‐curative surgical recurrence remains limited, making it challenging to determine the best follow‐up strategy and to detect the best treatment options as an adjuvant therapy for selected patients.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Mastrangelo L

Authors: Mastrangelo L, Cipressi C, Masetti M, Zanello M, Romboli A,

Keywords: nomogram, pancreatic neuroendocrine tumor, recurrence,

#2816 Germline Variants in Cancer Predisposing Genes in Young Adults with Neuroendocrine Tumors

Introduction: Advances in genomics have enabled the recognition of new cancer predisposing genes (CPG). There are few studies of CPG in neuroendocrine tumors (NET).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Riechelmann R

Authors: Riechelmann R, de Paula C, Donadio M, Barros M, Formiga M,

Keywords: hereditary syndrome, neuroendocrine tumors, germline variants,