Abstract Library

#3574 Multiple Endocrine Neoplasia type 1 (MEN1): A series of cases in an oncology department

Introduction: Multiple Endocrine Neoplasia type 1 is an autosomal dominant disorder characterized by parathyroid, pancreatic islet and pituitary tumors. Early diagnosis should be achieved in patients with MEN1.

Conference:

Presenting Author: Tsoukalas N

Authors: Tsoukalas N, Arvanitou E, Gkikas K, Malliopoulos D, Chatzelis E,

Keywords: Multiple Endocrine Neoplasia type 1, MEN1 syndrome, MEN1 gene, Neuroendocrine tumor, Multidisciplinary approach,

#3512 Genetic, epigenetic and/or transcriptional profiling of 14q genes, MAX and MEG3 in pituitary neuroendocrine tumors

Introduction: Recent studies have identified a growing series of susceptibility genes for pituitary neuroendocrine tumors (PitNETs) and pheochromocytomas/paragangliomas (PPGL). Some of these genes (e.g., SDH genes) have be specifically associated with the development of these pathologies.

Conference:

Presenting Author: Ibáñez Costa A

Authors: Ibáñez-Costa A, Letón R, Rivero-Cortés E, Álvarez-Escolá C, Rodriguez Poyo-Guerrero P,

Keywords: pituitary tumor, epigenetics, MAX, genomics,

#3108 Challenges in primary neuroendocrine tumor identification

Introduction: ACTH secreting neuroendocrine tumors can be a pituitary adenoma, an ectopic tumor, or very rarely - pituitary carcinoma. The identification of the primary neuroendocrine tumor can be challenging or even unsuccessful.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Butkus M

Authors: Sereikaitė L, Butkus M, Jasinskaitė M, Žilaitienė B,

Keywords: cushing syndrome, metastatic neuroendocrine tumor, pituitary adenoma, pituitary carcinoma,

#3079 Novel Symptoms and Therapy of Multiple Endocrine Neoplasia Type 1

Introduction: MEN1 is a rare autosomal inherited disease with hallmark of hyperparathyroidism, duodenopancreatic NENs and pituitary tumor.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: bai J

Authors: Bai J, Tang Q,

Keywords: MEN1, LGCS, NENs, gastrinoma, Parathyroid carcinoma,

#3062 The Splicing Factor CELF4 Is Dysregulated in Neuroendocrine Tumors, Where It Can Enhance Aggressiveness Features

Introduction: There is increasing evidence that alterations in alternative splicing are linked to key tumor features in different cancers. Besides mutations, dysregulation of the splicing machinery would represent the main underlying cause for these alterations. Indeed, splicing dysregulation is emerging as a novel, transversal cancer hallmark, due to its association with multiple dysfunctions in tumor cells.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Alors-Pérez E

Authors: Alors-Pérez E, Pedraza-Arévalo S, Vázquez-Borrego M, Blázquez-Encinas R, Herrera-Martínez A,

Keywords: PanNET, CELF4, splicing, aggressiveness, pituitary tumors,