A carcinoid heart revealing a neuroendocrine tumor

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Introduction: Carcinoid heart disease can occur in patients with a carcinoid tumor and is defined by the presence of right organic valve disease. These are mainly patients with carcinoid syndrome, often with delayed diagnosis. The difficulty of this pathology is due to its rarity and the fact that it involves several medical and surgical specialties.

Aim(s): We report the case of a neuroendocrine tumor discovered by a carcinoid heart with a review of the literature.

Materials and methods: 64year-old patient with no particular history who consulted for asthenia with slight respiratory discomfort without any other symptomatology. Cardiac ultrasound and cardiac MRI objectified dilation of the right chambers, tricuspid insufficiency with preserved right ventricle function, thoraco abdomino pelvic scan revealed multiples hepatic nodules. After biopsy anatomopathological and immunohisto chemical study the diagnosis neuroendocrine tumor has been made. It’s well-differentiated with grade II positive chromogranin A, synaptopysin, CD56 a mitotic index estimated at 7% and negative CK7 CK20. An octreoscan was done which showed only hyperfixation in the liver with no other site. Valve replacement is not currently indicated. The tumor was classified as metastatic with unknown primary.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Aliane H

Authors: Aliane H, Ghomari-Bezzar S,

Keywords: carcinoid heart, unknown primary, immunohistochemical, prognosis,