A rare case of oligometastatic thymic carcinoid

#3341

Introduction: Primary thymic neuroendocrine tumors (NETs) are a rare type of cancer which have a propensity to local or distant spread to nodes, lung, and bone. Treatment consists of a combination of surgery, SACT and radiotherapy, depending on the stage.

Aim(s): A 47-year-old male presented in 2018 with dyspnoea, chest pain and nausea. ECOG performance status was 0. CT chest showed a 10cm mediastinal mass with FDG-PET avidity in regional nodes. He underwent resection and histology showed well-differentiated atypical thymic carcinoid tumor with Ki67 10%, 8 mitosis per 10HPF, pT1aN1M0R1.

Materials and methods: He received 6 cycles of adjuvant streptozocin/capecitabine. A post treatment FDG PET revealed a T10 metastasis and a pancreatic body mass, with dotatate PET confirming uptake at T10 but no uptake in the pancreas. EUS-FNA of the pancreatic mass confirmed a well-differentiated NET, Ki67<2%. Despite histological comparison it was difficult to ascertain whether this pancreatic mass was a metachronous metastasis from the thymus or a second primary NET.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Cooper J

Authors: Cooper J, Jethwa D, Zen Y, Prachalis A, Taylor B,

Keywords: thymic carcinoid, oligometastatic disease,