Enhanced Prognostication of Grade 1 Small Bowel Neuroendocrine Tumours with Multi-Parametric Clinicopathological Assessment

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Introduction: Most small bowel neuroendocrine tumours (SBNET) are Grade 1 (G1), and exhibit at least nodal metastasis at diagnosis. The clinical behaviours of G1 SBNET remain poorly predictable. The ‘NET nomogram’ developed by Modlin et al. designates SBNET as low/medium/high risk by mathematical analysis of 15 clinicopathological parameters.

Aim(s): To compare the prognostic power of staging and the NET nomogram in G1 SBNET.

Materials and methods: Retrospective case review of 62 surgical G1 SBNET patients from 2 tertiary centres. Tumours were categorized low/medium/high risk based on nomogram scores. Survival analyses utilised Kaplan-Meier.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Clift A

Authors: Clift A, Faiz O, Goldin R, Martin J, Wasan H,

Keywords: nomogram, stage, grade,