Gastric neuroendocrine neoplasms in younger patients: A retrospective single-centre study

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Introduction: Gastric neuroendocrine neoplasms (gNENs) are rare neoplasms arising from stomach enterochromaffin-like (ECL) cells. Type I gNENs are the most common type, typically indolent and arising in the context of chronic atrophic gastritis (CAG). While type I gNENs are generally diagnosed in pts over 50, their occurrence in younger pts raises concern about the onset of CAG-related complications at an earlier age, potentially affecting tumour growth and clinical outcomes. Young-oriented studies on type I gNETs are still lacking in literature.

Aim(s): Evaluate the clinical characteristics of type I gNENs diagnosed in pts under 50, searching for potential age-related features.

Materials and methods: A single ENETS Center of Excellence retrospective observational study included consecutive pts with type I gNEN diagnosed at an age younger than 50. Data on pts comorbidities and tumour characteristics were collected.

Conference:

Presenting Author:

Authors: Romano E, Rinzivillo M, Marasco M, Dell' Unto E, Esposito G,

Keywords: Gastric neuroendocrine neoplasm, Young adults, Chronic Atrophic Gastritis,