Gastrointestinal Neuroendocrine Tumors of Unknown Primary Site: Report from a Series at a Single Institute


Introduction: Neuroendocrine neoplasms of unknown primary (NENs-UP) account for 10-13% of all NENs and show different biologic behavior, histologic appearance and clinical outcome.

Aim(s): To describe clinical, histologic characteristics and the diagnostic work-up of NENs-UP.

Materials and methods: Between 2005 and 2015, among 93 metastatic NENs, 17 (11M; median age 64 yrs) presented with histologically proven NENs-UP.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Zilli A

Authors: Massironi S, Fanetti I, Cavalcoli F, Zilli A, Conte D,

Keywords: Neuroendocrine tumors, unknown primary,

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