Management and outcomes of malignant paragangliomas and phaeochromocytomas

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Introduction: Chromaffin-cell tumors include phaeochromocytomas and paragangliomas, represent a rare group of neuroendocrine tumors and are located in adrenal medulla or extra-adrenal sites, respectively. Ten percent of phaeochromocytomas and 15-35% of paragangliomas are malignant.

Aim(s): To review the management and outcome of a series of malignant paragangliomas/phaeochromocytomas diagnosed and treated in our unit.

Materials and methods: Twenty-three patients (11 patients with paragangliomas and 12 patients with phaeochromocytomas) were included. Tumor histology was assessed according to ENETS Guidelines. Response to therapy was assessed clinically and radiologically according to the RECIST criteria.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: TOUMPANAKIS C

Authors: Warner B, Chilkunda D, Khan M, Buscombe J, Caplin M,

Keywords: paragangliomas, phaeochromocytomas, chromaffin-cell tumours,