Novel morphological tools in predicting pancreatic neuroendocrine tumors (Pan-Net) clinical outcome

#3468

Introduction: Pancreatic Neuroendocrine Tumor (Pan-NET) clinical outcome shows a high variability among patients within the same World Health Organization (WHO) category. To date, there is a lack of markers to predict recurrence after resection, which makes it difficult to identify patients with higher risk of progression.

Aim(s): To evaluate morphologic and clinicopathological features of surgically resected Pan-NET.

Materials and methods: Surgical specimens of 150 Pan-NET patients were evaluated for the following diagnostic and prognostic tools: Tumor stage, Ki-67, parenchymal infiltration, neural and vascular invasion, tumor necrosis or sclerosis and tumor deposits. These data were correlated with Overall Survival (OS) and stage I-II-III Disease-Free Survival (DFS).

Conference:

Presenting Author:

Authors: Lagano V, Sabella G, Cattaneo L, Grillo F, Mangogna A,

Keywords: Pancreas, parenchymal infiltration, tumor deposits,