Prognostic and diagnostic value of serum 5-HIAA in well-differentiated neuroendocrine neoplasms

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Introduction: There are only few studies on the diagnostic value of serum 5HIAA as compared to the 24-hours urinary sampling method and a lack of evidence on the prognostic significance of its serum levels, as well as the markers' ability to predict changes in disease status.

Aim(s): Our aim was to investigate the clinical utility of serum 5HIAA for diagnostic purposes and disease surveillance in a cohort of patients with well-differentiated neuroendocrine neoplasms (WD-NENs).

Materials and methods: Forty-eight patients with WD-NENs and concurrent serum and urinary 5HIAA testing as well as CT/MRI imaging were included.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Wedin M

Authors: Wedin M, Mehta S, Angerås-Kraftling J, Wallin G, Daskalakis K,

Keywords: biomarker, serum 5HIAA, well-differentiated NEN,