Abstract Library

#4133 Clinical impact and prognosis of patients with Si-NET and bone metastases – Do they matter?

Introduction: The prevalence of bone metastases (BM) in small intestinal neuroendocrine tumors (Si-NET) ranges from 5 to 23 %.

Conference:

Presenting Author: Wedin M

Authors: Wedin M, Daskalakis K, Tiensuu Janson E, Sundin A, Wallin G,

Keywords: bone metastases, si-net, Neuroendocrine Neoplasm,

#3810 A patient with BRAF V600E mutated colon-NEC showing response to BRAF- and MEK inhibitors

Introduction: Preclinical studies have reported that the BRAF V600E mutation is a druggable target in colorectal neuroendocrine carcinomas (NECs). At least one case report has presented clinical success in the treatment of colorectal NEC using a BRAF inhibitor.

Conference:

Presenting Author:

Authors: Falkman L, Sundin A, Crona J, Wallin G, Welin S,

Keywords: neuroendocrine carcinoma, BRAF V600E, dabrafenib, trametinib, colorectal nec,

#3731 Rare metastases diagnosed on 68Ga-DOTATOC-PET/CT in small intestinal and pancreatic NETs

Introduction: Neuroendocrine metastases to the orbita, heart, breast, bone, Virchow's lymph node, and pancreas are rarely encountered in small intestinal (SI-NETs) and pancreatic NETs (P-NETs).

Conference:

Presenting Author: Wedin M

Authors: Wedin M, Daskalakis K, Wallin G, Sundin A, Tiensuu Janson E,

Keywords: Neuroendocrine Neoplasm, Rare metastases, Bone metastases, breast metastases, orbita metastases, heart metastases, Lung and pleural metastases, Pancreatic metastases,

#3545 Virchow's node metastasis from small intestinal neuroendocrine neoplasms: A bi-center cohort study

Introduction: Small Intestinal Neuroendocrine Neoplasms (SI-NENs) may rarely metastasize to the left supraclavicular lymph nodes, also known as Virchow’s node metastasis (VM).

Conference:

Presenting Author: Wedin M

Authors: Wedin M, Tsoli M, Wallin G, Janson E, Koumarianou A,

Keywords: Virchow's node metastasis, Small intestinal NEN,

#3171 Prognostic and diagnostic value of serum 5-HIAA in well-differentiated neuroendocrine neoplasms

Introduction: There are only few studies on the diagnostic value of serum 5HIAA as compared to the 24-hours urinary sampling method and a lack of evidence on the prognostic significance of its serum levels, as well as the markers' ability to predict changes in disease status.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Wedin M

Authors: Wedin M, Mehta S, Angerås-Kraftling J, Wallin G, Daskalakis K,

Keywords: biomarker, serum 5HIAA, well-differentiated NEN,