Abstract Library
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ENETS Abstract Search
Introduction: NENs are rare tumors and can grow in almost all tissues. Regardless histological, molecular and imaging characteristics that are indicative of the primary origin, a significant percentage remain of unknown primary.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Koumarianou A
Authors: Koumarianou A, Tsoukalas N, Syrigos K, Demiri S, Ziras N,
Keywords: NeuroEndocrine Neoplasms (NENs), epidemiological features, registry, diagnosis, Hellenic Society of Medical Oncology (HeSMO),
Introduction: Metastatic or inoperable NeuroEndocrine Neoplasms (NENs) are unresponsive to chemotherapy and targeted therapies. An emerging option is PRRT.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Liotsou T
Authors: Liotsou T, Stefanoyiannis A, Alexandraki K, Koumarianou A, Angelousi A,
Introduction: Malignant gastroenteropancreatic neuroendocrine tumors (GEPNETS), mainly carcinoids, are not considered to be particularly chemotherapy-sensitive to conventional chemotherapeutic schemes. Long-standing evidence suggests these tumors to be highly vascularised and responsive to antiangiogenic strategies. Newest reports demonstrate benefit by the use of temozolamide, an oral alkylating agent similar to intravenous dacarbazine. The DNA repair enzyme O6-alkylguanine–DNA alkyltransferase (AGAT) confers cancer cell resistance to O6-alkylating agents such as temozolamide through its ability to remove methyl/alkyl groups from the O6-position of guanine, thus correcting drug-induced DNA damage.
Conference: 7th Annual ENETSConcerence (2010)
Presenting Author:
Authors: Koumarianou A, Zilos A, Syrios J, Kanakis G, Antoniou S,
Keywords: GEPNETs, temozolamide, bevacizumab, somatostatin analogue,