Reduced 25-OH-Vitamin D Levels in Patients with Chronic Autoimmune Atrophic Gastritis


Introduction: Chronic atrophic autoimmune gastritis (CAAG) is characterized by parietal cells disruption leading to hypochlorhydria and vitamin B12 malabsorption. An increased risk of osteoporosis was reported in patients with long-standing hypochlorhydria. Only few studies reported a possible association between CAAG and 25OHVitamin D (25OHvitD) deficiency.

Aim(s): To evaluate the prevalence of 25OHvitD deficiency in CAAG.

Materials and methods: From 2012 to 2015, 25OHVitD and calcium were measured in all the CAAG patients followed at our Centre. Results were compared with a group of 1234 subjects (958 F; median age 62 yrs). Subjects with abnormal calcium values, known VitD supplementation, primary hyperparathyroidism or renal failure were excluded.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Cavalcoli F

Authors: Cavalcoli F, Zilli A, Bernasconi S, Conte D, Ciafardini C,

Keywords: vitamin D, CAAG,

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